Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies

The interconnected network of pathways downstream of the TGFβ, WNT and EGF-families of receptor ligands play an important role in colorectal cancer pathogenesis. We studied and implemented dynamic simulations of multiple downstream pathways and described the section of the signaling network consider...

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Detalles Bibliográficos
Autores principales: Tortolina, Lorenzo, Duffy, David J., Maffei, Massimo, Castagnino, Nicoletta, Carmody, Aimée M., Kolch, Walter, Kholodenko, Boris N., Ambrosi, Cristina De, Barla, Annalisa, Biganzoli, Elia M., Nencioni, Alessio, Patrone, Franco, Ballestrero, Alberto, Zoppoli, Gabriele, Verri, Alessandro, Parodi, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467132/
https://www.ncbi.nlm.nih.gov/pubmed/25671297

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