Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers

Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamous cell carcinoma (HNSCC). In the present study, we investigated whether garcinol, a polyisoprenylated benzophenone can chemosensitize HNSCC to cisplat...

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Detalles Bibliográficos
Autores principales: Li, Feng, Shanmugam, Muthu K., Siveen, Kodappully Sivaraman, Wang, Fan, Ong, Tina H., Loo, Ser Yue, Swamy, Mahadeva M.M., Mandal, Somnath, Kumar, Alan Prem, Goh, Boon Cher, Kundu, Tapas, Ahn, Kwang Seok, Wang, Ling Zhi, Hui, Kam Man, Sethi, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467139/
https://www.ncbi.nlm.nih.gov/pubmed/25762616

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