Cargando…

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype

Proteomic analysis identified differentially expressed proteins between zoledronic acid-resistant and aggressive DU145R80 prostate cancer (PCa) cells and their parental DU145 cells. Ingenuity Pathway Analysis (IPA) showed a strong relationship between the identified proteins within a network associa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milone, Maria Rita, Pucci, Biagio, Bifulco, Katia, Iannelli, Federica, Lombardi, Rita, Chiara, Ciardiello, Bruzzese, Francesca, Carriero, Maria Vincenza, Budillon, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467152/ https://www.ncbi.nlm.nih.gov/pubmed/25481874

Ejemplares similares

Annexin A1 is involved in the acquisition and maintenance of a stem cell-like/aggressive phenotype in prostate cancer cells with acquired resistance to zoledronic acid
por: Bizzarro, Valentina, et al.
Publicado: (2015)

Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition
por: Iannelli, Federica, et al.
Publicado: (2020)

HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer
por: Lombardi, Rita, et al.
Publicado: (2021)

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation
por: Ciardiello, Chiara, et al.
Publicado: (2019)

Epigenetic Approaches to Overcome Fluoropyrimidines Resistance in Solid Tumors
por: Grumetti, Laura, et al.
Publicado: (2022)

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways
por: Bruzzese, F, et al.
Publicado: (2013)

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells
por: Milone, M R, et al.
Publicado: (2013)

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells
por: Milone, M R, et al.
Publicado: (2014)

Valproic Acid Synergizes With Cisplatin and Cetuximab in vitro and in vivo in Head and Neck Cancer by Targeting the Mechanisms of Resistance
por: Iannelli, Federica, et al.
Publicado: (2020)

Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models
por: Cocco, Stefania, et al.
Publicado: (2022)

The Crosstalk between Cancer Stem Cells and Microenvironment Is Critical for Solid Tumor Progression: The Significant Contribution of Extracellular Vesicles
por: Ciardiello, Chiara, et al.
Publicado: (2018)

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression
por: Ciardiello, Chiara, et al.
Publicado: (2016)

Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches
por: Leone, Alessandra, et al.
Publicado: (2017)

Structure-function relationship of an Urokinase Receptor-derived peptide which inhibits the Formyl Peptide Receptor type 1 activity
por: Minopoli, Michele, et al.
Publicado: (2019)

Cyclization of the Urokinase Receptor-Derived Ser-Arg-Ser-Arg-Tyr Peptide Generates a Potent Inhibitor of Trans-Endothelial Migration of Monocytes
por: Yousif, Ali Munaim, et al.
Publicado: (2015)

Inhibiting Monocyte Recruitment to Prevent the Pro-Tumoral Activity of Tumor-Associated Macrophages in Chondrosarcoma
por: Minopoli, Michele, et al.
Publicado: (2020)

The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells
por: Colangelo, T, et al.
Publicado: (2016)

Controversial Role of Kisspeptins/KiSS-1R Signaling System in Tumor Development
por: Fratangelo, Federica, et al.
Publicado: (2018)

Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence
por: Bifulco, Katia, et al.
Publicado: (2014)

HDAC class I inhibitor domatinostat sensitizes pancreatic cancer to chemotherapy by targeting cancer stem cell compartment via FOXM1 modulation
por: Roca, Maria Serena, et al.
Publicado: (2022)

Correction to: HDAC class I inhibitor domatinostat sensitizes pancreatic cancer to chemotherapy by targeting cancer stem cell compartment via FOXM1 modulation
por: Roca, Maria Serena, et al.
Publicado: (2022)

Identification and Targeting of Stem Cell-Activated Pathways in Cancer Therapy
por: Budillon, Alfredo, et al.
Publicado: (2019)

Involvement of the Soluble Urokinase Receptor in Chondrosarcoma Cell Mobilization
por: Bifulco, Katia, et al.
Publicado: (2011)

Spontaneous cancer remission after COVID-19: insights from the pandemic and their relevance for cancer treatment
por: Meo, Concetta, et al.
Publicado: (2023)

Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53
por: Terranova-Barberio, Manuela, et al.
Publicado: (2017)

Single Amino Acid Substitutions in the Chemotactic Sequence of Urokinase Receptor Modulate Cell Migration and Invasion
por: Bifulco, Katia, et al.
Publicado: (2012)

Evaluation of Selenite Effects on Selenoproteins and Cytokinome in Human Hepatoma Cell Lines
por: Rusolo, Fabiola, et al.
Publicado: (2013)

Unveiling the Trypanosoma cruzi Nuclear Proteome
por: dos Santos Júnior, Agenor de Castro Moreira, et al.
Publicado: (2015)

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma
por: Fattore, Luigi, et al.
Publicado: (2018)

Low-dose zoledronate for the treatment of bone metastasis secondary to prostate cancer
por: Akoury, Elie, et al.
Publicado: (2019)

Analgesic efficacy of zoledronic acid and its effect on functional status of prostate cancer patients with metastasis
por: Gálvez, Rafael, et al.
Publicado: (2008)

Microsoft Windows 7 unveiled: exposing the latest features and functions that set Windows 7 apart from its predecessors
por: Bruzzese, J Peter
Publicado: (2010)

A Proteomic Platform Unveils the Brain Glycogen Phosphorylase as a Potential Therapeutic Target for Glioblastoma Multiforme
por: Ferraro, Giusy, et al.
Publicado: (2022)

The urokinase receptor-derived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells
por: Ingangi, Vincenzo, et al.
Publicado: (2016)

Unveiling the Link between Prostatitis and Periodontitis
por: Boyapati, Ramanarayana, et al.
Publicado: (2018)

Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas
por: Carriero, Maria Vincenza, et al.
Publicado: (2017)

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma
por: Salaroglio, Iris Chiara, et al.
Publicado: (2014)

An Integrated In Silico, In Vitro and Tumor Tissues Study Identified Selenoprotein S (SELENOS) and Valosin-Containing Protein (VCP/p97) as Novel Potential Associated Prognostic Biomarkers in Triple Negative Breast Cancer
por: Costantini, Susan, et al.
Publicado: (2022)

Integrated Analysis to Study the Relationship between Tumor-Associated Selenoproteins: Focus on Prostate Cancer
por: Capone, Francesca, et al.
Publicado: (2020)

New Insights into the Occurrence of Matrix Metalloproteases -2 and -9 in a Cohort of Breast Cancer Patients and Proteomic Correlations
por: Di Cara, Gianluca, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6suh8mb9uuoiaen1sp3f5b82uo