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Pex11mediates peroxisomal proliferation by promoting deformation of the lipid membrane

Pex11p family proteins are key players in peroxisomal fission, but their molecular mechanisms remains mostly unknown. In the present study, overexpression of Pex11pβ caused substantial vesiculation of peroxisomes in mammalian cells. This vesicle formation was dependent on dynamin-like protein 1 (DLP...

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Detalles Bibliográficos
Autores principales: Yoshida, Yumi, Niwa, Hajime, Honsho, Masanori, Itoyama, Akinori, Fujiki, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467191/
https://www.ncbi.nlm.nih.gov/pubmed/25910939
http://dx.doi.org/10.1242/bio.201410801