miR-17 inhibition enhances the formation of kidney cancer spheres with stem cell/tumor initiating cell properties

Renal cell carcinoma (RCC) is an aggressive disease, with 35% chance of metastasis. The ‘cancer stem cell’ hypothesis suggests that a subset of cancer cells possess stem cell properties and is crucial in tumor initiation, metastasis and treatment resistance. We isolated RCC spheres and showed that t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lichner, Zsuzsanna, Saleh, Carol, Subramaniam, Venkateswaran, Seivwright, Annetta, Prud'homme, Gerald Joseph, Yousef, George Makram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467387/
https://www.ncbi.nlm.nih.gov/pubmed/25011053

Ejemplares similares

Ejemplares similares