Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling

O-glycosylation is a common protein modification. Aberrant O-glycosylation is associated with many cancers. GALNT1 is a GalNAc-transferase that initiates protein O-glycosylation. We found that GALNT1 is frequently up-regulated in hepatocellular carcinoma (HCC) and is associated with poor patient sur...

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Detalles Bibliográficos
Autores principales: Huang, Miao-Juei, Hu, Rey-Heng, Chou, Chih-Hsing, Hsu, Chia-Lang, Liu, Ya-Wen, Huang, John, Hung, Ji-Shiang, Lai, I-Rue, Juan, Hsueh-Fen, Yu, Sung-Liang, Wu, Yao-Ming, Huang, Min-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467392/
https://www.ncbi.nlm.nih.gov/pubmed/25730904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467392/
https://www.ncbi.nlm.nih.gov/pubmed/25730904

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