EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma

LMP1, which is encoded by the Epstein-Barr virus, is proposed to be one of the major oncogenic factors involved in nasopharyngeal carcinoma (NPC). Previous studies demonstrated that down-regulation of LMP1 by LMP1-targeted DNAzyme (DZ1) increases the radiosensitivity of NPC. However, the mechanism b...

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Detalles Bibliográficos
Autores principales: Yang, Lifang, Liu, Liyu, Xu, Zhijie, Liao, Weihua, Feng, Deyun, Dong, Xin, Xu, San, Xiao, Lanbo, Lu, Jingchen, Luo, Xiangjian, Tang, Min, Bode, Ann M., Dong, Zigang, Sun, Lunquan, Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467403/
https://www.ncbi.nlm.nih.gov/pubmed/25714020

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