Granzyme M expressed by tumor cells promotes chemoresistance and EMT in vitro and metastasis in vivo associated with STAT3 activation

Granzyme M is a serine protease known to be often expressed by natural killer cells and induce target cells apoptosis in combination with perforin. However, we detected granzyme M expression in murine and human cancer cell lines and human tumor samples in our study. Granzyme M increased chemoresista...

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Detalles Bibliográficos
Autores principales: Wang, Huiru, Sun, Qing, Wu, Yanhong, Wang, Lin, Zhou, Chunxia, Ma, Wenbo, Zhang, Youhui, Wang, Shengdian, Zhang, Shuren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467404/
https://www.ncbi.nlm.nih.gov/pubmed/25788270

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