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Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathway
Aberrant glycosylation is frequently observed in cancers. Core 1 β1,3-galactosyltransferase (C1GALT1) is an exclusive enzyme in humans that catalyzes the biosynthesis of core 1 O-glycan structure, Gal-GalNAc-O-Ser/Thr, whose expression is commonly up-regulated during tumorigenesis. Little is known a...
Autores principales: | Chou, Chih-Hsing, Huang, Miao-Juei, Chen, Chi-Hau, Shyu, Ming-Kwang, Huang, John, Hung, Ji-Shiang, Huang, Chiun-Sheng, Huang, Min-Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467426/ https://www.ncbi.nlm.nih.gov/pubmed/25762620 |
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