ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells

The presence of circulating tumor cells (CTCs) in blood predicts poor patient outcome and CTC frequency is correlated with higher risk of metastasis. Recently discovered, novel microtubule-based structures, microtentacles, can enhance reattachment of CTCs to the vasculature. Microtentacles are highl...

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Detalles Bibliográficos
Autores principales: Bhandary, Lekhana, Whipple, Rebecca A., Vitolo, Michele I., Charpentier, Monica S., Boggs, Amanda E., Chakrabarti, Kristi R., Thompson, Keyata N., Martin, Stuart S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467435/
https://www.ncbi.nlm.nih.gov/pubmed/25749040

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