FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells

Epithelial-mesenchymal transition (EMT) plays a fundamental role in cancer metastasis. The ubiquitin ligase FBXW7, a general tumor suppressor in human cancer, has been implicated in diverse cellular processes, however, its role in cholangiocarcinoma (CCA) metastasis has not been identified. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Hui, Lu, Xiaofei, Liu, Ziming, Chen, Lili, Xu, Yunfei, Wang, Yuli, Wei, Guangwei, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467439/
https://www.ncbi.nlm.nih.gov/pubmed/25749036

Ejemplares similares

Ejemplares similares