MicroRNA-3127 promotes cell proliferation and tumorigenicity in hepatocellular carcinoma by disrupting of PI3K/AKT negative regulation

Recent studies have shown that multiple phosphatases deactivate the PI3K/AKT signaling pathway. Here we demonstrated that, by suppressing multiple phosphatases, miR-3127 promotes growth of hepatocellular carcinoma (HCC). Our study also reveals clinical significance of miR-3127 expression in HCC pati...

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Detalles Bibliográficos
Autores principales: Jiang, Jianxin, Zhang, Yi, Guo, Yuting, Yu, Chao, Chen, Meiyuan, Li, Zhu, Tian, Se, Sun, Chengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467442/
https://www.ncbi.nlm.nih.gov/pubmed/25849943

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