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Pyruvate Carboxylase Is Up-Regulated in Breast Cancer and Essential to Support Growth and Invasion of MDA-MB-231 Cells

Pyruvate carboxylase (PC) is an anaplerotic enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, which is crucial for replenishing tricarboxylic acid cycle intermediates when they are used for biosynthetic purposes. We examined the expression of PC by immunohistochemistry of paraffin...

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Detalles Bibliográficos
Autores principales:	Phannasil, Phatchariya, Thuwajit, Chanitra, Warnnissorn, Malee, Wallace, John C., MacDonald, Michael J., Jitrapakdee, Sarawut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467472/ https://www.ncbi.nlm.nih.gov/pubmed/26070193 http://dx.doi.org/10.1371/journal.pone.0129848

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