Monocyte Tumor Necrosis Factor-α–Converting Enzyme Catalytic Activity and Substrate Shedding in Sepsis and Noninfectious Systemic Inflammation*

OBJECTIVES: To determine the effect of severe sepsis on monocyte tumor necrosis factor-α–converting enzyme baseline and inducible activity profiles. DESIGN: Observational clinical study. SETTING: Mixed surgical/medical teaching hospital ICU. PATIENTS: Sixteen patients with severe sepsis, 15 healthy...

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Detalles Bibliográficos
Autores principales: O’Callaghan, David J. P., O’Dea, Kieran P., Scott, Alasdair J., Takata, Masao, Gordon, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Feature Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467590/
https://www.ncbi.nlm.nih.gov/pubmed/25867908
http://dx.doi.org/10.1097/CCM.0000000000000992

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