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Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants
Biological performance of artificial implant materials is closely related to their surface characteristics, such as microtopography, and composition. Therefore, convenient fabrication of artificial implant materials with a cell-friendly surface structure and suitable composition was of great signifi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467738/ https://www.ncbi.nlm.nih.gov/pubmed/26089665 http://dx.doi.org/10.2147/IJN.S75999 |
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author | Wang, Hui Lai, Yue-Kun Zheng, Ru-Yue Bian, Ye Zhang, Ke-Qin Lin, Chang-Jian |
author_facet | Wang, Hui Lai, Yue-Kun Zheng, Ru-Yue Bian, Ye Zhang, Ke-Qin Lin, Chang-Jian |
author_sort | Wang, Hui |
collection | PubMed |
description | Biological performance of artificial implant materials is closely related to their surface characteristics, such as microtopography, and composition. Therefore, convenient fabrication of artificial implant materials with a cell-friendly surface structure and suitable composition was of great significance for current tissue engineering. In this work, titanate materials with a nanotubular structure were successfully fabricated through a simple chemical treatment. Immersion test in a simulated body fluid and in vitro cell culture were used to evaluate the biological performance of the treated samples. The results demonstrate that the titanate layer with a nanotubular structure on Ti substrates can promote the apatite-inducing ability remarkably and greatly enhance cellular responses. This highlights the potential of such titanate biomaterials with the special nanoscale structure and effective surface composition for biomedical applications such as bone implants. |
format | Online Article Text |
id | pubmed-4467738 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-44677382015-06-18 Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants Wang, Hui Lai, Yue-Kun Zheng, Ru-Yue Bian, Ye Zhang, Ke-Qin Lin, Chang-Jian Int J Nanomedicine Original Research Biological performance of artificial implant materials is closely related to their surface characteristics, such as microtopography, and composition. Therefore, convenient fabrication of artificial implant materials with a cell-friendly surface structure and suitable composition was of great significance for current tissue engineering. In this work, titanate materials with a nanotubular structure were successfully fabricated through a simple chemical treatment. Immersion test in a simulated body fluid and in vitro cell culture were used to evaluate the biological performance of the treated samples. The results demonstrate that the titanate layer with a nanotubular structure on Ti substrates can promote the apatite-inducing ability remarkably and greatly enhance cellular responses. This highlights the potential of such titanate biomaterials with the special nanoscale structure and effective surface composition for biomedical applications such as bone implants. Dove Medical Press 2015-06-08 /pmc/articles/PMC4467738/ /pubmed/26089665 http://dx.doi.org/10.2147/IJN.S75999 Text en © 2015 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Wang, Hui Lai, Yue-Kun Zheng, Ru-Yue Bian, Ye Zhang, Ke-Qin Lin, Chang-Jian Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants |
title | Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants |
title_full | Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants |
title_fullStr | Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants |
title_full_unstemmed | Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants |
title_short | Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants |
title_sort | tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467738/ https://www.ncbi.nlm.nih.gov/pubmed/26089665 http://dx.doi.org/10.2147/IJN.S75999 |
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