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Low-dose Arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation
Most chemotherapeutical drugs kill cancer cells chiefly by inducing DNA damage, which unfortunately also causes undesirable injuries to normal tissues, mainly due to p53 activation. We report a novel strategy of normal tissue-protection that involves p53/NF-κB coordinated metabolic regulation. Pretr...
Autores principales: | Ganapathy, Suthakar, Xiao, Shaowen, Seo, Seog-Jin, Lall, Rajuli, Yang, Mei, Xu, Teng, Su, Hang, Shadfan, Miriam, Ha, Chul S., Yuan, Zhi-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467814/ https://www.ncbi.nlm.nih.gov/pubmed/23524579 http://dx.doi.org/10.1038/onc.2013.81 |
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