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Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease
The nitroheterocyclic drugs nifurtimox and benznidazole are first-line drugs available to treat Chagas disease; however, they have limitations, including long treatment courses and toxicity. Strategies to overcome these limitations include the identification of new drugs with specific target profile...
Autores principales: | Assíria Fontes Martins, Tassiane, de Figueiredo Diniz, Lívia, Mazzeti, Ana Lia, da Silva do Nascimento, Álvaro Fernando, Caldas, Sérgio, Caldas, Ivo Santana, de Andrade, Isabel Mayer, Ribeiro, Isabela, Bahia, Maria Terezinha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468053/ https://www.ncbi.nlm.nih.gov/pubmed/26076455 http://dx.doi.org/10.1371/journal.pone.0128707 |
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