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In silico Analysis and Experimental Validation of Lignan Extracts from Kadsura longipedunculata for Potential 5-HT1AR Agonists

OBJECTIVES: Kadsura longipedunculata (KL) has been widely used for the treatment of insomnia in traditional Chinese medicine. The aim of this study was to explore the mechanism of the sedative and hypnotic effects of KL. MATERIALS AND METHODS: The content of KL was evaluated by HPLC-TOF-MS, and a po...

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Detalles Bibliográficos
Autores principales:	Zheng, Yaxin, Wu, Jiming, Feng, Xuesong, Jia, Ying, Huang, Jian, Hao, Zhihui, Zhao, Songyan, Wang, Jinhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468062/ https://www.ncbi.nlm.nih.gov/pubmed/26076134 http://dx.doi.org/10.1371/journal.pone.0130055

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