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Adeno-Associated Virus Vector Mediated Delivery of the HBV Genome Induces Chronic Hepatitis B Virus Infection and Liver Fibrosis in Mice

Liver cirrhosis and hepatocellular carcinomas are major health problems of chronic hepatitis B virus (HBV) infection. To date, rare model has reproduced liver fibrosis associated with long-term HBV infection which in turn has hindered both the understanding of HBV biology and the development of new...

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Detalles Bibliográficos
Autores principales:	Ye, Lei, Yu, Haisheng, Li, Chengwen, Hirsch, Matthew L., Zhang, Liguo, Samulski, R. Jude, Li, Wuping, Liu, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468063/ https://www.ncbi.nlm.nih.gov/pubmed/26075890 http://dx.doi.org/10.1371/journal.pone.0130052

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