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Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes

Autoimmune diabetes mellitus (DM) results from the destruction of pancreatic islet cells by activated T lymphocytes, which have been primed by activated dendritic cells (DC). Individualized therapy with ex vivo DC manipulation and reinfusion has been proposed as a treatment for DM, but this treatmen...

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Detalles Bibliográficos
Autores principales:	Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Promessi, Victor J., Shyu, Luke, Sheng, Caroline, Kang, McNancy, Cottam, Howard B., Carson, Dennis A., Corr, Maripat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468074/ https://www.ncbi.nlm.nih.gov/pubmed/26076454 http://dx.doi.org/10.1371/journal.pone.0129867

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