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2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline

Heparan sulfate (HS) is a linear carbohydrate composed of polymerized uronate-glucosamine disaccharide units that decorates cell surface and secreted glycoproteins in the extracellular matrix. In mammals HS is subjected to differential sulfation by fifteen different heparan sulfotransferase (HST) en...

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Detalles Bibliográficos
Autores principales:	Chan, Wai Kit, Howe, Katherine, Clegg, James M., Guimond, Scott E., Price, David J., Turnbull, Jeremy E., Pratt, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468130/ https://www.ncbi.nlm.nih.gov/pubmed/26075383 http://dx.doi.org/10.1371/journal.pone.0130147

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