Cargando…

DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity

Retroviral integrases (INs) catalyse the integration of the reverse transcribed viral DNA into the host cell genome. This process is selective, and chromatin has been proposed to be a major factor regulating this step in the viral life cycle. However, the precise underlying mechanisms are still unde...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naughtin, Monica, Haftek-Terreau, Zofia, Xavier, Johan, Meyer, Sam, Silvain, Maud, Jaszczyszyn, Yan, Levy, Nicolas, Miele, Vincent, Benleulmi, Mohamed Salah, Ruff, Marc, Parissi, Vincent, Vaillant, Cédric, Lavigne, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468133/ https://www.ncbi.nlm.nih.gov/pubmed/26075397 http://dx.doi.org/10.1371/journal.pone.0129427

Ejemplares similares

Intasome architecture and chromatin density modulate retroviral integration into nucleosome
por: Benleulmi, Mohamed Salah, et al.
Publicado: (2015)

Functional Coupling between HIV-1 Integrase and the SWI/SNF Chromatin Remodeling Complex for Efficient in vitro Integration into Stable Nucleosomes
por: Lesbats, Paul, et al.
Publicado: (2011)

Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
por: Benleulmi, Mohamed S., et al.
Publicado: (2017)

Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import
por: Cribier, Alexandra, et al.
Publicado: (2011)

DNA physical properties determine nucleosome occupancy from yeast to fly
por: Miele, Vincent, et al.
Publicado: (2008)

Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration
por: Matysiak, Julien, et al.
Publicado: (2017)

Transposable element-derived sequences in vertebrate development
por: Etchegaray, Ema, et al.
Publicado: (2021)

The Neurodevelopmental Gene MSANTD2 Belongs to a Gene Family Formed by Recurrent Molecular Domestication of Harbinger Transposons at the Base of Vertebrates
por: Etchegaray, Ema, et al.
Publicado: (2022)

Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase
por: Mauro, Eric, et al.
Publicado: (2019)

The C-Terminal Domain of HIV-1 Integrase: A Swiss Army Knife for the Virus?
por: Rocchi, Cecilia, et al.
Publicado: (2022)

Targeting the Nucleosome Acidic Patch by Viral Proteins: Two Birds with One Stone?
por: Lagadec, Floriane, et al.
Publicado: (2022)

Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75
por: Lapaillerie, Delphine, et al.
Publicado: (2021)

GCN2 phosphorylates HIV-1 integrase and decreases HIV-1 replication by limiting viral integration
por: Jaspart, A., et al.
Publicado: (2017)

HIV-1 integrase crosslinked oligomers are active in vitro
por: Faure, Aurélie, et al.
Publicado: (2005)

DNA minicircles clarify the specific role of DNA structure on retroviral integration
por: Pasi, Marco, et al.
Publicado: (2016)

In Vitro Recombination Catalyzed by Bacterial Class 1 Integron Integrase IntI1 Involves Cooperative Binding and Specific Oligomeric Intermediates
por: Dubois, Véronique, et al.
Publicado: (2009)

Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
por: Escudero, Jose Antonio, et al.
Publicado: (2016)

The HIV-1 Integrase α4-Helix Involved in LTR-DNA Recognition Is also a Highly Antigenic Peptide Element
por: Azzi, Sandy, et al.
Publicado: (2010)

Efficient and Specific Internal Cleavage of a Retroviral Palindromic DNA Sequence by Tetrameric HIV-1 Integrase
por: Delelis, Olivier, et al.
Publicado: (2007)

Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration
por: Thierry, Sylvain, et al.
Publicado: (2015)

The HIV-1 Integrase C-Terminal Domain Induces TAR RNA Structural Changes Promoting Tat Binding
por: Rocchi, Cecilia, et al.
Publicado: (2022)

The HIV-1 Integrase Mutations Y143C/R Are an Alternative Pathway for Resistance to Raltegravir and Impact the Enzyme Functions
por: Reigadas, Sandrine, et al.
Publicado: (2010)

TOX4 and NOVA1 Proteins Are Partners of the LEDGF PWWP Domain and Affect HIV-1 Replication
por: Morchikh, Mehdi, et al.
Publicado: (2013)

Coupling between Sequence-Mediated Nucleosome Organization and Genome Evolution
por: Barbier, Jérémy, et al.
Publicado: (2021)

Carboxylate-functionalized foldamer inhibitors of HIV-1 integrase and Topoisomerase 1: artificial analogues of DNA mimic proteins
por: Corvaglia, Valentina, et al.
Publicado: (2019)

Small-angle X-ray characterization of the nucleoprotein complexes resulting from DNA-induced oligomerization of HIV-1 integrase
por: Baranova, Svetlana, et al.
Publicado: (2007)

Structural and functional studies of HIV-1 pre-integration complexes
por: Ruff, Marc, et al.
Publicado: (2014)

Modulation of the functional interfaces between retroviral intasomes and the human nucleosome
por: Mauro, E., et al.
Publicado: (2023)

Structural and functional studies of the HIV-1 pre-integration complex
por: Levy, Nicolas, et al.
Publicado: (2013)

In vitro initial attachment of HIV-1 integrase to viral ends: control of the DNA specific interaction by the oligomerization state
por: Lesbats, P., et al.
Publicado: (2008)

Chromosomal integration of LTR-flanked DNA in yeast expressing HIV-1 integrase: down regulation by RAD51
por: Desfarges, S., et al.
Publicado: (2006)

Replication landscape of the human genome
por: Petryk, Nataliya, et al.
Publicado: (2016)

Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors
por: Malet, Isabelle, et al.
Publicado: (2017)

Natural Stilbenoids Isolated from Grapevine Exhibiting Inhibitory Effects against HIV-1 Integrase and Eukaryote MOS1 Transposase In Vitro Activities
por: Pflieger, Aude, et al.
Publicado: (2013)

Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase
por: Bonnard, Damien, et al.
Publicado: (2023)

Integrase and integration: biochemical activities of HIV-1 integrase
por: Delelis, Olivier, et al.
Publicado: (2008)

HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors
por: Koneru, Pratibha C, et al.
Publicado: (2019)

In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors
por: Ni, Xiaoju, et al.
Publicado: (2012)

Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
por: Le Rouzic, Erwann, et al.
Publicado: (2013)

Nucleosome Dynamics: a new tool for the dynamic analysis of nucleosome positioning
por: Buitrago, Diana, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_50hjlohava7gkebcsttfoijinr