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Sample Size Estimation for Non-Inferiority Trials: Frequentist Approach versus Decision Theory Approach

BACKGROUND: Non-inferiority trials are performed when the main therapeutic effect of the new therapy is expected to be not unacceptably worse than that of the standard therapy, and the new therapy is expected to have advantages over the standard therapy in costs or other (health) consequences. These...

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Detalles Bibliográficos
Autores principales: Bouman, A. C., ten Cate-Hoek, A. J., Ramaekers, B. L. T., Joore, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468148/
https://www.ncbi.nlm.nih.gov/pubmed/26076354
http://dx.doi.org/10.1371/journal.pone.0130531