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Murine Efficacy and Pharmacokinetic Evaluation of the Flaviviral NS5 Capping Enzyme 2-Thioxothiazolidin-4-One Inhibitor BG-323

Arthropod-borne flavivirus infection continues to cause significant morbidity and mortality worldwide. Identification of drug targets and novel antiflaviviral compounds to treat these diseases has become a global health imperative. A previous screen of 235,456 commercially available small molecules...

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Detalles Bibliográficos
Autores principales:	Bullard, Kristen M., Gullberg, Rebekah C., Soltani, Elnaz, Steel, J. Jordan, Geiss, Brian J., Keenan, Susan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468182/ https://www.ncbi.nlm.nih.gov/pubmed/26075394 http://dx.doi.org/10.1371/journal.pone.0130083

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