Cargando…
Connexin43 Mediated Delivery of ADAMTS5 Targeting siRNAs from Mesenchymal Stem Cells to Synovial Fibroblasts
Osteoarthritis is a joint-destructive disease that has no effective cure. Human mesenchymal stem cells (hMSCs) could offer therapeutic benefit in the treatment of arthritic diseases by suppressing inflammation and permitting tissue regeneration, but first these cells must overcome the catabolic envi...
Autores principales: | Liu, Shuo, Niger, Corinne, Koh, Eugene Y., Stains, Joseph P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468185/ https://www.ncbi.nlm.nih.gov/pubmed/26076025 http://dx.doi.org/10.1371/journal.pone.0129999 |
Ejemplares similares
-
Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture
por: Gupta, Aditi, et al.
Publicado: (2014) -
Interaction of connexin43 and protein kinase C-delta during FGF2 signaling
por: Niger, Corinne, et al.
Publicado: (2010) -
VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts
por: Pérez‐García, Selene, et al.
Publicado: (2016) -
Connexin43 Hemichannel-Mediated Regulation of Connexin43
por: Li, Kai, et al.
Publicado: (2013) -
Lentiviral-mediated delivery of siRNAs for antiviral therapy
por: Morris, K V, et al.
Publicado: (2006)