Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC

The recent FDA approval of the MiSeqDx platform provides a unique opportunity to develop targeted next generation sequencing (NGS) panels for human disease, including cancer. We have developed a scalable, targeted panel-based assay termed UNCseq, which involves a NGS panel of over 200 cancer-associa...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaobei, Wang, Anyou, Walter, Vonn, Patel, Nirali M., Eberhard, David A., Hayward, Michele C., Salazar, Ashley H., Jo, Heejoon, Soloway, Matthew G., Wilkerson, Matthew D., Parker, Joel S., Yin, Xiaoying, Zhang, Guosheng, Siegel, Marni B., Rosson, Gary B., Earp, H. Shelton, Sharpless, Norman E., Gulley, Margaret L., Weck, Karen E., Hayes, D. Neil, Moschos, Stergios J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468211/
https://www.ncbi.nlm.nih.gov/pubmed/26076459
http://dx.doi.org/10.1371/journal.pone.0129280

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