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Inhibiting the Activity of CA1 Hippocampal Neurons Prevents the Recall of Contextual Fear Memory in Inducible ArchT Transgenic Mice

The optogenetic manipulation of light-activated ion-channels/pumps (i.e., opsins) can reversibly activate or suppress neuronal activity with precise temporal control. Therefore, optogenetic techniques hold great potential to establish causal relationships between specific neuronal circuits and their...

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Detalles Bibliográficos
Autores principales: Sakaguchi, Masanori, Kim, Karam, Yu, Lily Mae Yee, Hashikawa, Yoshiko, Sekine, Yukiko, Okumura, Yuki, Kawano, Masako, Hayashi, Masanobu, Kumar, Deependra, Boyden, Edward S., McHugh, Thomas J., Hayashi, Yasunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468217/
https://www.ncbi.nlm.nih.gov/pubmed/26075894
http://dx.doi.org/10.1371/journal.pone.0130163