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Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

Oncogenic KRas reprograms pancreatic ductal adenocarcinoma (PDAC) cells to states which are highly resistant to apoptosis. Thus, a major preclinical goal is to identify effective strategies for killing PDAC cells. Artesunate (ART) is an anti-malarial that specifically induces programmed cell death i...

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Detalles Bibliográficos
Autores principales:	Eling, Nils, Reuter, Lukas, Hazin, John, Hamacher-Brady, Anne, Brady, Nathan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468338/ https://www.ncbi.nlm.nih.gov/pubmed/26097885

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