Transmembrane-Bound IL-15–Promoted Epithelial-Mesenchymal Transition in Renal Cancer Cells Requires the Src-Dependent Akt/GSK-3β/β-Catenin Pathway()()

Intrarenal interleukin-15 (IL-15) plays a major role controlling epithelial survival and polarization both in physiological and pathologic conditions. Herein, we confirmed that human renal cell carcinomas (RCCs) express a membrane-bound IL-15 isoform displaying an unusual molecular weight of 27 kDa....

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Huaqin, Meng, Xiaoxin, Guo, Wenjie, Cai, Peifen, Li, Wanshuai, Li, Qian, Wang, Weicheng, Sun, Yang, Xu, Qiang, Gu, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468369/
https://www.ncbi.nlm.nih.gov/pubmed/26025664
http://dx.doi.org/10.1016/j.neo.2015.04.002

Ejemplares similares

Ejemplares similares