Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability

More than 20 distinct gene loci have so far been implicated in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder characterized by progressive neurodegeneration of motor neurons (MN) and death. Most of this distinct set of ALS-related proteins undergoes toxic deposition specific...

Descripción completa

Detalles Bibliográficos
Autores principales: Leal, Sónia S., Gomes, Cláudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468822/
https://www.ncbi.nlm.nih.gov/pubmed/26136661
http://dx.doi.org/10.3389/fncel.2015.00225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468822/
https://www.ncbi.nlm.nih.gov/pubmed/26136661
http://dx.doi.org/10.3389/fncel.2015.00225

Ejemplares similares