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Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability
More than 20 distinct gene loci have so far been implicated in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder characterized by progressive neurodegeneration of motor neurons (MN) and death. Most of this distinct set of ALS-related proteins undergoes toxic deposition specific...
Autores principales: | Leal, Sónia S., Gomes, Cláudio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468822/ https://www.ncbi.nlm.nih.gov/pubmed/26136661 http://dx.doi.org/10.3389/fncel.2015.00225 |
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