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Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

Ras (Rat sarcoma) protein is a central regulator of cell growth and proliferation. Mutations in the RAS gene are known to occur in human cancers and have been shown to contribute to carcinogenesis. In this study, we show that the multifunctional-autoprocessing repeats-in-toxin (MARTX) toxin-effector...

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Detalles Bibliográficos
Autores principales:	Antic, Irena, Biancucci, Marco, Zhu, Yueming, Gius, David R., Satchell, Karla J. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468845/ https://www.ncbi.nlm.nih.gov/pubmed/26051945 http://dx.doi.org/10.1038/ncomms8396

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