Airway bacteria measured by quantitative polymerase chain reaction and culture in patients with stable COPD: relationship with neutrophilic airway inflammation, exacerbation frequency, and lung function

BACKGROUND: Potentially pathogenic microorganisms can be detected by quantitative real-time polymerase chain reaction (qPCR) in sputum from patients with COPD, although how this technique relates to culture and clinical measures of disease is unclear. We used cross-sectional and longitudinal data to...

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Detalles Bibliográficos
Autores principales: Bafadhel, Mona, Haldar, Koirobi, Barker, Bethan, Patel, Hemu, Mistry, Vijay, Barer, Michael R, Pavord, Ian D, Brightling, Christopher E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468933/
https://www.ncbi.nlm.nih.gov/pubmed/26089657
http://dx.doi.org/10.2147/COPD.S80091

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