A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas

BACKGROUND: In previous years, immunotoxins have been shown to be a greatly promising therapeutic tool for brain malignancies, such as gliomas. Human mesenchymal stem cells (hMSCs) exhibit tropism to tumor tissue. However, the effect of bispecific immunotoxins in malignant gliomas is still unknown....

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Detalles Bibliográficos
Autores principales: Zhang, Yonghong, Sun, Xinlin, Huang, Min, Ke, Yiquan, Wang, Jihui, Liu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468939/
https://www.ncbi.nlm.nih.gov/pubmed/26089644
http://dx.doi.org/10.2147/DDDT.S79475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468939/
https://www.ncbi.nlm.nih.gov/pubmed/26089644
http://dx.doi.org/10.2147/DDDT.S79475

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