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The aging-disease false dichotomy: understanding senescence as pathology

From a biological perspective aging (senescence) appears to be a form of complex disease syndrome, though this is not the traditional view. This essay aims to foster a realistic understanding of aging by scrutinizing ideas old and new. The conceptual division between aging-related diseases and an un...

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Detalles Bibliográficos
Autor principal: Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468941/
https://www.ncbi.nlm.nih.gov/pubmed/26136770
http://dx.doi.org/10.3389/fgene.2015.00212
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author Gems, David
author_facet Gems, David
author_sort Gems, David
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description From a biological perspective aging (senescence) appears to be a form of complex disease syndrome, though this is not the traditional view. This essay aims to foster a realistic understanding of aging by scrutinizing ideas old and new. The conceptual division between aging-related diseases and an underlying, non-pathological aging process underpins various erroneous traditional ideas about aging. Among biogerontologists, another likely error involves the aspiration to treat the entire aging process, which recent advances suggest is somewhat utopian. It also risks neglecting a more modest but realizable goal: to develop preventative treatments that partially protect against aging.
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spelling pubmed-44689412015-07-01 The aging-disease false dichotomy: understanding senescence as pathology Gems, David Front Genet Genetics From a biological perspective aging (senescence) appears to be a form of complex disease syndrome, though this is not the traditional view. This essay aims to foster a realistic understanding of aging by scrutinizing ideas old and new. The conceptual division between aging-related diseases and an underlying, non-pathological aging process underpins various erroneous traditional ideas about aging. Among biogerontologists, another likely error involves the aspiration to treat the entire aging process, which recent advances suggest is somewhat utopian. It also risks neglecting a more modest but realizable goal: to develop preventative treatments that partially protect against aging. Frontiers Media S.A. 2015-06-16 /pmc/articles/PMC4468941/ /pubmed/26136770 http://dx.doi.org/10.3389/fgene.2015.00212 Text en Copyright © 2015 Gems. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Gems, David
The aging-disease false dichotomy: understanding senescence as pathology
title The aging-disease false dichotomy: understanding senescence as pathology
title_full The aging-disease false dichotomy: understanding senescence as pathology
title_fullStr The aging-disease false dichotomy: understanding senescence as pathology
title_full_unstemmed The aging-disease false dichotomy: understanding senescence as pathology
title_short The aging-disease false dichotomy: understanding senescence as pathology
title_sort aging-disease false dichotomy: understanding senescence as pathology
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468941/
https://www.ncbi.nlm.nih.gov/pubmed/26136770
http://dx.doi.org/10.3389/fgene.2015.00212
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