Cargando…
The aging-disease false dichotomy: understanding senescence as pathology
From a biological perspective aging (senescence) appears to be a form of complex disease syndrome, though this is not the traditional view. This essay aims to foster a realistic understanding of aging by scrutinizing ideas old and new. The conceptual division between aging-related diseases and an un...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468941/ https://www.ncbi.nlm.nih.gov/pubmed/26136770 http://dx.doi.org/10.3389/fgene.2015.00212 |
_version_ | 1782376571871428608 |
---|---|
author | Gems, David |
author_facet | Gems, David |
author_sort | Gems, David |
collection | PubMed |
description | From a biological perspective aging (senescence) appears to be a form of complex disease syndrome, though this is not the traditional view. This essay aims to foster a realistic understanding of aging by scrutinizing ideas old and new. The conceptual division between aging-related diseases and an underlying, non-pathological aging process underpins various erroneous traditional ideas about aging. Among biogerontologists, another likely error involves the aspiration to treat the entire aging process, which recent advances suggest is somewhat utopian. It also risks neglecting a more modest but realizable goal: to develop preventative treatments that partially protect against aging. |
format | Online Article Text |
id | pubmed-4468941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-44689412015-07-01 The aging-disease false dichotomy: understanding senescence as pathology Gems, David Front Genet Genetics From a biological perspective aging (senescence) appears to be a form of complex disease syndrome, though this is not the traditional view. This essay aims to foster a realistic understanding of aging by scrutinizing ideas old and new. The conceptual division between aging-related diseases and an underlying, non-pathological aging process underpins various erroneous traditional ideas about aging. Among biogerontologists, another likely error involves the aspiration to treat the entire aging process, which recent advances suggest is somewhat utopian. It also risks neglecting a more modest but realizable goal: to develop preventative treatments that partially protect against aging. Frontiers Media S.A. 2015-06-16 /pmc/articles/PMC4468941/ /pubmed/26136770 http://dx.doi.org/10.3389/fgene.2015.00212 Text en Copyright © 2015 Gems. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Gems, David The aging-disease false dichotomy: understanding senescence as pathology |
title | The aging-disease false dichotomy: understanding senescence as pathology |
title_full | The aging-disease false dichotomy: understanding senescence as pathology |
title_fullStr | The aging-disease false dichotomy: understanding senescence as pathology |
title_full_unstemmed | The aging-disease false dichotomy: understanding senescence as pathology |
title_short | The aging-disease false dichotomy: understanding senescence as pathology |
title_sort | aging-disease false dichotomy: understanding senescence as pathology |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468941/ https://www.ncbi.nlm.nih.gov/pubmed/26136770 http://dx.doi.org/10.3389/fgene.2015.00212 |
work_keys_str_mv | AT gemsdavid theagingdiseasefalsedichotomyunderstandingsenescenceaspathology AT gemsdavid agingdiseasefalsedichotomyunderstandingsenescenceaspathology |