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CT brush and CancerZap!: two video games for computed tomography dose minimization

BACKGROUND: X-ray dose from computed tomography (CT) scanners has become a significant public health concern. All CT scanners spray x-ray photons across a patient, including those using compressive sensing algorithms. New technologies make it possible to aim x-ray beams where they are most needed to...

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Detalles Bibliográficos
Autores principales: Alvare, Graham, Gordon, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469010/
https://www.ncbi.nlm.nih.gov/pubmed/25962597
http://dx.doi.org/10.1186/s12976-015-0003-4
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author Alvare, Graham
Gordon, Richard
author_facet Alvare, Graham
Gordon, Richard
author_sort Alvare, Graham
collection PubMed
description BACKGROUND: X-ray dose from computed tomography (CT) scanners has become a significant public health concern. All CT scanners spray x-ray photons across a patient, including those using compressive sensing algorithms. New technologies make it possible to aim x-ray beams where they are most needed to form a diagnostic or screening image. We have designed a computer game, CT Brush, that takes advantage of this new flexibility. It uses a standard MART algorithm (Multiplicative Algebraic Reconstruction Technique), but with a user defined dynamically selected subset of the rays. The image appears as the player moves the CT brush over an initially blank scene, with dose accumulating with every “mouse down” move. The goal is to find the “tumor” with as few moves (least dose) as possible. RESULTS: We have successfully implemented CT Brush in Java and made it available publicly, requesting crowdsourced feedback on improving the open source code. With this experience, we also outline a “shoot ‘em up game” CancerZap! for photon limited CT. CONCLUSIONS: We anticipate that human computing games like these, analyzed by methods similar to those used to understand eye tracking, will lead to new object dependent CT algorithms that will require significantly less dose than object independent nonlinear and compressive sensing algorithms that depend on sprayed photons. Preliminary results suggest substantial dose reduction is achievable. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12976-015-0003-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-44690102015-06-17 CT brush and CancerZap!: two video games for computed tomography dose minimization Alvare, Graham Gordon, Richard Theor Biol Med Model Software BACKGROUND: X-ray dose from computed tomography (CT) scanners has become a significant public health concern. All CT scanners spray x-ray photons across a patient, including those using compressive sensing algorithms. New technologies make it possible to aim x-ray beams where they are most needed to form a diagnostic or screening image. We have designed a computer game, CT Brush, that takes advantage of this new flexibility. It uses a standard MART algorithm (Multiplicative Algebraic Reconstruction Technique), but with a user defined dynamically selected subset of the rays. The image appears as the player moves the CT brush over an initially blank scene, with dose accumulating with every “mouse down” move. The goal is to find the “tumor” with as few moves (least dose) as possible. RESULTS: We have successfully implemented CT Brush in Java and made it available publicly, requesting crowdsourced feedback on improving the open source code. With this experience, we also outline a “shoot ‘em up game” CancerZap! for photon limited CT. CONCLUSIONS: We anticipate that human computing games like these, analyzed by methods similar to those used to understand eye tracking, will lead to new object dependent CT algorithms that will require significantly less dose than object independent nonlinear and compressive sensing algorithms that depend on sprayed photons. Preliminary results suggest substantial dose reduction is achievable. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12976-015-0003-4) contains supplementary material, which is available to authorized users. BioMed Central 2015-05-12 /pmc/articles/PMC4469010/ /pubmed/25962597 http://dx.doi.org/10.1186/s12976-015-0003-4 Text en © Alvare and Gordon. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Software
Alvare, Graham
Gordon, Richard
CT brush and CancerZap!: two video games for computed tomography dose minimization
title CT brush and CancerZap!: two video games for computed tomography dose minimization
title_full CT brush and CancerZap!: two video games for computed tomography dose minimization
title_fullStr CT brush and CancerZap!: two video games for computed tomography dose minimization
title_full_unstemmed CT brush and CancerZap!: two video games for computed tomography dose minimization
title_short CT brush and CancerZap!: two video games for computed tomography dose minimization
title_sort ct brush and cancerzap!: two video games for computed tomography dose minimization
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469010/
https://www.ncbi.nlm.nih.gov/pubmed/25962597
http://dx.doi.org/10.1186/s12976-015-0003-4
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