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Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis
The Type I interferons (IFN), beta (IFN-β) and the alpha family (IFN-α), act through a common receptor and have anti-inflammatory effects. IFN-β is used to treat multiple sclerosis (MS) and is effective against experimental autoimmune encephalomyelitis (EAE), an animal model for MS. Mice with EAE sh...
Autores principales: | Khorooshi, Reza, Mørch, Marlene Thorsen, Holm, Thomas Hellesøe, Berg, Carsten Tue, Dieu, Ruthe Truong, Dræby, Dina, Issazadeh-Navikas, Shohreh, Weiss, Siegfried, Lienenklaus, Stefan, Owens, Trevor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469095/ https://www.ncbi.nlm.nih.gov/pubmed/25869642 http://dx.doi.org/10.1007/s00401-015-1418-z |
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