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High-resolution characterization of sequence signatures due to non-random cleavage of cell-free DNA

BACKGROUND: High-throughput sequencing of cell-free DNA fragments found in human plasma has been used to non-invasively detect fetal aneuploidy, monitor organ transplants and investigate tumor DNA. However, many biological properties of this extracellular genetic material remain unknown. Research th...

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Detalles Bibliográficos
Autores principales: Chandrananda, Dineika, Thorne, Natalie P., Bahlo, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469119/
https://www.ncbi.nlm.nih.gov/pubmed/26081108
http://dx.doi.org/10.1186/s12920-015-0107-z