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High-resolution characterization of sequence signatures due to non-random cleavage of cell-free DNA
BACKGROUND: High-throughput sequencing of cell-free DNA fragments found in human plasma has been used to non-invasively detect fetal aneuploidy, monitor organ transplants and investigate tumor DNA. However, many biological properties of this extracellular genetic material remain unknown. Research th...
Autores principales: | Chandrananda, Dineika, Thorne, Natalie P., Bahlo, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469119/ https://www.ncbi.nlm.nih.gov/pubmed/26081108 http://dx.doi.org/10.1186/s12920-015-0107-z |
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