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The T cell antigen receptor: the Swiss army knife of the immune system

The mammalian T cell receptor (TCR) orchestrates immunity by responding to many billions of different ligands that it has never encountered before and cannot adapt to at the protein sequence level. This remarkable receptor exists in two main heterodimeric isoforms: αβ TCR and γδ TCR. The αβ TCR is e...

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Detalles Bibliográficos
Autores principales: Attaf, M, Legut, M, Cole, D K, Sewell, A K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469151/
https://www.ncbi.nlm.nih.gov/pubmed/25753381
http://dx.doi.org/10.1111/cei.12622