Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology

BACKGROUND: Combination drugs containing an angiotensin receptor blocker and a calcium channel blocker have been widely commercialized in recent years, and their advantages, such as improvements in adherence, and reductions in medication costs, have been greatly emphasized. However, the actual situa...

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Autores principales: Kato, Hideki, Shiraishi, Takeshi, Ueda, Shuko, Kubo, Eiji, Shima, Tomoko, Nagura, Michito, Yano, Hirofumi, Izumikawa, Yuh, Shimada, Masaru, Tomioka, Satoru, Nosaka, Hitonari, Kojima, Kenichiro, Tanemoto, Masayuki, Uchida, Shunya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469305/
https://www.ncbi.nlm.nih.gov/pubmed/25135635
http://dx.doi.org/10.1007/s10157-014-1017-7
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author Kato, Hideki
Shiraishi, Takeshi
Ueda, Shuko
Kubo, Eiji
Shima, Tomoko
Nagura, Michito
Yano, Hirofumi
Izumikawa, Yuh
Shimada, Masaru
Tomioka, Satoru
Nosaka, Hitonari
Kojima, Kenichiro
Tanemoto, Masayuki
Uchida, Shunya
author_facet Kato, Hideki
Shiraishi, Takeshi
Ueda, Shuko
Kubo, Eiji
Shima, Tomoko
Nagura, Michito
Yano, Hirofumi
Izumikawa, Yuh
Shimada, Masaru
Tomioka, Satoru
Nosaka, Hitonari
Kojima, Kenichiro
Tanemoto, Masayuki
Uchida, Shunya
author_sort Kato, Hideki
collection PubMed
description BACKGROUND: Combination drugs containing an angiotensin receptor blocker and a calcium channel blocker have been widely commercialized in recent years, and their advantages, such as improvements in adherence, and reductions in medication costs, have been greatly emphasized. However, the actual situations and the impact of switching to combination drugs in clinical practice of nephrology are not fully understood. METHODS: This study was conducted in outpatients of nephrology who received antihypertensive medicines, and who switched to combination drugs. Changes in the potency of the antihypertensive drugs, and blood pressure were examined retrospectively before and after changing treatments. In addition, the study also involved patients’ questionnaire, which examined changes in blood pressure at home, the presence or absence of missed doses, the impact on medication-related expenses, and the level of patients’ satisfaction with regard to combination drugs. RESULTS: Survey results from 90 participants revealed that changing to combination drugs resulted in a reduction of missed doses, a decrease in blood pressure measured in an outpatient setting, and a reduction in medication-related expenses in total patients, non-chronic kidney disease (CKD) patients, and CKD patients. CONCLUSION: Our study shows that switching to combination antihypertensive drugs resulted in an improvement in adherence and a reduction in medication-related expenses, and revealed that patient satisfaction was high. Combination drugs for hypertensive patients may be beneficial in both medical and economical viewpoints.
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spelling pubmed-44693052015-06-17 Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology Kato, Hideki Shiraishi, Takeshi Ueda, Shuko Kubo, Eiji Shima, Tomoko Nagura, Michito Yano, Hirofumi Izumikawa, Yuh Shimada, Masaru Tomioka, Satoru Nosaka, Hitonari Kojima, Kenichiro Tanemoto, Masayuki Uchida, Shunya Clin Exp Nephrol Original Article BACKGROUND: Combination drugs containing an angiotensin receptor blocker and a calcium channel blocker have been widely commercialized in recent years, and their advantages, such as improvements in adherence, and reductions in medication costs, have been greatly emphasized. However, the actual situations and the impact of switching to combination drugs in clinical practice of nephrology are not fully understood. METHODS: This study was conducted in outpatients of nephrology who received antihypertensive medicines, and who switched to combination drugs. Changes in the potency of the antihypertensive drugs, and blood pressure were examined retrospectively before and after changing treatments. In addition, the study also involved patients’ questionnaire, which examined changes in blood pressure at home, the presence or absence of missed doses, the impact on medication-related expenses, and the level of patients’ satisfaction with regard to combination drugs. RESULTS: Survey results from 90 participants revealed that changing to combination drugs resulted in a reduction of missed doses, a decrease in blood pressure measured in an outpatient setting, and a reduction in medication-related expenses in total patients, non-chronic kidney disease (CKD) patients, and CKD patients. CONCLUSION: Our study shows that switching to combination antihypertensive drugs resulted in an improvement in adherence and a reduction in medication-related expenses, and revealed that patient satisfaction was high. Combination drugs for hypertensive patients may be beneficial in both medical and economical viewpoints. Springer Japan 2014-08-19 2015 /pmc/articles/PMC4469305/ /pubmed/25135635 http://dx.doi.org/10.1007/s10157-014-1017-7 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Kato, Hideki
Shiraishi, Takeshi
Ueda, Shuko
Kubo, Eiji
Shima, Tomoko
Nagura, Michito
Yano, Hirofumi
Izumikawa, Yuh
Shimada, Masaru
Tomioka, Satoru
Nosaka, Hitonari
Kojima, Kenichiro
Tanemoto, Masayuki
Uchida, Shunya
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology
title Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology
title_full Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology
title_fullStr Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology
title_full_unstemmed Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology
title_short Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology
title_sort blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469305/
https://www.ncbi.nlm.nih.gov/pubmed/25135635
http://dx.doi.org/10.1007/s10157-014-1017-7
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