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Does Tyrosyl DNA Phosphodiesterase-2 Play a Role in Hepatitis B Virus Genome Repair?

Hepatitis B virus (HBV) replication and persistence are sustained by a nuclear episome, the covalently closed circular (CCC) DNA, which serves as the transcriptional template for all viral RNAs. CCC DNA is converted from a relaxed circular (RC) DNA in the virion early during infection as well as fro...

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Detalles Bibliográficos
Autores principales: Cui, Xiuji, McAllister, Rebecca, Boregowda, Rajeev, Sohn, Ji A., Ledesma, Felipe Cortes, Caldecott, Keith W., Seeger, Christoph, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469307/
https://www.ncbi.nlm.nih.gov/pubmed/26079492
http://dx.doi.org/10.1371/journal.pone.0128401