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Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides

BACKGROUND: SIVmac239 is a commonly used virus in non-human primate models of HIV transmission and pathogenesis. Previous studies identified four suboptimal nucleotides in the SIVmac239 genome, which putatively inhibit its replicative capacity. Since all four suboptimal changes revert to the optimal...

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Detalles Bibliográficos
Autores principales: Fennessey, Christine M, Reid, Carolyn, Lipkey, Leslie, Newman, Laura, Oswald, Kelli, Piatak, Michael, Roser, James D, Chertova, Elena, Smedley, Jeremy, Gregory Alvord, W., Del Prete, Gregory Q, Estes, Jacob D, Lifson, Jeffrey D, Keele, Brandon F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469405/
https://www.ncbi.nlm.nih.gov/pubmed/26076651
http://dx.doi.org/10.1186/s12977-015-0175-3