Cargando…

Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides

BACKGROUND: SIVmac239 is a commonly used virus in non-human primate models of HIV transmission and pathogenesis. Previous studies identified four suboptimal nucleotides in the SIVmac239 genome, which putatively inhibit its replicative capacity. Since all four suboptimal changes revert to the optimal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fennessey, Christine M, Reid, Carolyn, Lipkey, Leslie, Newman, Laura, Oswald, Kelli, Piatak, Michael, Roser, James D, Chertova, Elena, Smedley, Jeremy, Gregory Alvord, W., Del Prete, Gregory Q, Estes, Jacob D, Lifson, Jeffrey D, Keele, Brandon F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469405/ https://www.ncbi.nlm.nih.gov/pubmed/26076651 http://dx.doi.org/10.1186/s12977-015-0175-3

Ejemplares similares

AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity
por: Fuchs, Sebastian P., et al.
Publicado: (2015)

Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques
por: Gonzalez-Nieto, Lucas, et al.
Publicado: (2019)

Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir
por: Immonen, Taina T., et al.
Publicado: (2021)

P03-08. Protection against SIVmac239 challenge in a rhesus macaque model conferred by a doxycycline dependent attenuated SIVmac239
por: Page, M, et al.
Publicado: (2009)

Non-neutralizing Antibodies May Contribute to Suppression of SIVmac239 Viremia in Indian Rhesus Macaques
por: Pedreño-Lopez, Nuria, et al.
Publicado: (2021)

Evolution of SIVmac239 following serial passaging in humanized mice
por: Curlin, James Z., et al.
Publicado: (2022)

Regulatory role of upstream AUG codons within the SIVmac239 genome
por: van der Velden, Gisela J, et al.
Publicado: (2011)

Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy
por: Fennessey, Christine M., et al.
Publicado: (2017)

Defining early SIV replication and dissemination dynamics following vaginal transmission
por: Deleage, Claire, et al.
Publicado: (2019)

CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells
por: Klatt, Nichole R., et al.
Publicado: (2010)

Dendritic cell subsets dynamics and cytokine production in SIVmac239-infected Chinese rhesus macaques
por: Xia, Hou-Jun, et al.
Publicado: (2010)

Rapid, repeated, low-dose challenges with SIVmac239 infect animals in a condensed challenge window
por: Greene, Justin M, et al.
Publicado: (2014)

T cell response specificity and magnitude against SIVmac239 are not concordant in major histocompatibility complex-matched animals
por: Cain, Brian T, et al.
Publicado: (2013)

Parasites may exit immunocompromised northern pig-tailed macaques (Macaca leonina) infected with SIVmac239
por: Song, Tian-Zhang, et al.
Publicado: (2018)

Comprehensive mapping of SIVmac239 envelope antigenic determinants recognized by specific polyclonal antibodies in vaccinated and/or infected macaques
por: Guo, J, et al.
Publicado: (2012)

Generation of Neutralizing Antibodies and Divergence of SIVmac239 in Cynomolgus Macaques Following Short-Term Early Antiretroviral Therapy
por: Özkaya Şahin, Gülşen, et al.
Publicado: (2010)

Insights into the Dual Activity of SIVmac239 Vif against Human and African Green Monkey APOBEC3G
por: Gaur, Ritu, et al.
Publicado: (2012)

Longitudinal white matter alterations in SIVmac239-infected rhesus monkeys with and without regular cART treatment
por: Liu, Jiaojiao, et al.
Publicado: (2023)

Disparate effects of acute and chronic infection with SIVmac239 or SHIV-89.6P on macaque plasmacytoid dendritic cells
por: Reeves, R. Keith, et al.
Publicado: (2007)

Effect of Plasma Viremia on Apoptosis and Immunophenotype of Dendritic Cells Subsets in Acute SIVmac239 Infection of Chinese Rhesus Macaques
por: Xia, Hou-Jun, et al.
Publicado: (2011)

A new strategy for repeated application of adenovirus based vectors: proof-of-concept in rhesus macaques challenged with SIVmac239
por: Sun, C, et al.
Publicado: (2012)

CD8+ and CD4+ cytotoxic T cell escape mutations precede breakthrough SIVmac239 viremia in an elite controller
por: Burwitz, Benjamin J, et al.
Publicado: (2012)

Rhesus Cytomegalovirus-Specific CD8(+) Cytotoxic T Lymphocytes Do Not Become Functionally Exhausted in Chronic SIVmac239 Infection
por: Rosen, Brandon C., et al.
Publicado: (2020)

Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission
por: Smedley, Jeremy, et al.
Publicado: (2014)

Correction: Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission
por: Smedley, Jeremy, et al.
Publicado: (2023)

Efficacy of vaccine-induced Vif-specific CTL responses against SIVmac239 infection: implications for antigen design in AIDS vaccines
por: Iwamoto, N, et al.
Publicado: (2012)

P03-06. Preserved cellular and humoral immune responses in macaques infected with SIVmac239 and subjected to early antiretroviral therapy
por: Makitalo, B, et al.
Publicado: (2009)

Location and Dynamics of the Immunodominant CD8 T Cell Response to SIVΔnef Immunization and SIVmac251 Vaginal Challenge
por: Sasikala-Appukuttan, Arun K., et al.
Publicado: (2013)

Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence
por: Zheng, Hong-Yi, et al.
Publicado: (2017)

Glucose Metabolism Disorder Induces Spermatogenic Dysfunction in Northern Pig-Tailed Macaques (Macaca leonina) With Long-Term SIVmac239 Infection
por: Song, Tian-Zhang, et al.
Publicado: (2021)

Immunization with Single-Cycle SIV Significantly Reduces Viral Loads After an Intravenous Challenge with SIV(mac)239
por: Jia, Bin, et al.
Publicado: (2009)

Antibodies to the envelope protein protect macaques from SIVmac251 acquisition in an immunization regimen that mimics the RV-144 Thai trial
por: Franchini, G, et al.
Publicado: (2012)

Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nef core domain bound to different-length TCRζ fragments
por: Kim, Walter M., et al.
Publicado: (2010)

An Automated Fluorescence-Based Method to Isolate Bone Marrow-Derived Plasma Cells from Rhesus Macaques Using SIVmac239 SOSIP.664
por: Pedreño-Lopez, Nuria, et al.
Publicado: (2020)

A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products
por: Shin, Young C., et al.
Publicado: (2018)

Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes
por: Srinivasakumar, Narasimhachar
Publicado: (2008)

Immunogenicity of Seven New Recombinant Yellow Fever Viruses 17D Expressing Fragments of SIVmac239 Gag, Nef, and Vif in Indian Rhesus Macaques
por: Martins, Mauricio A., et al.
Publicado: (2013)

Superior intestinal integrity and limited microbial translocation are associated with lower immune activation in SIVmac239-infected northern pig-tailed macaques (Macaca leonina)
por: Zhang, Ming-Xu, et al.
Publicado: (2019)

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection
por: Hao, Xing Pei, et al.
Publicado: (2015)

P19-55 LB. Effective control of a pathogenic SIVmac239 challenge by a novel heterologous mucosal prime and intramuscular boost vaccine strategy
por: Chen, Z, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_cln8nukb9etpk4voqjankbuln2