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The Associations between RNA Splicing Complex Gene SF3A1 Polymorphisms and Colorectal Cancer Risk in a Chinese Population

BACKGROUND: Aberrant alternative splicing included alterations in components of the mRNA splicing machinery often occurred in colon cancer. However, the role of SF3A1, one key component of the mRNA splicing machinery, on colorectal cancer (CRC) risk was still not elucidated. METHOD AND FINDINGS: We...

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Detalles Bibliográficos
Autores principales: Chen, Xiaohua, Du, Hua, Liu, Binjian, Zou, Li, Chen, Wei, Yang, Yang, Zhu, Ying, Gong, Yajie, Tian, Jianbo, Li, Feng, Zhong, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469430/
https://www.ncbi.nlm.nih.gov/pubmed/26079486
http://dx.doi.org/10.1371/journal.pone.0130377