Spontaneous Intestinal Tumorigenesis in Apc (/Min+) Mice Requires Altered T Cell Development with IL-17A

The control of inflammatory diseases requires functional regulatory T cells (Tregs) with significant Gata-3 expression. Here we address the inhibitory role of Tregs on intestinal tumorigenesis in the Apc (/Min+) mouse model that resembles human familial adenomatous polyposis (FAP). Apc (/Min+) mice...

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Detalles Bibliográficos
Autores principales: Chae, Wook-Jin, Bothwell, Alfred L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469837/
https://www.ncbi.nlm.nih.gov/pubmed/26146642
http://dx.doi.org/10.1155/2015/860106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469837/
https://www.ncbi.nlm.nih.gov/pubmed/26146642
http://dx.doi.org/10.1155/2015/860106

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