Cargando…

Clinical applications of next generation sequencing in cancer: from panels, to exomes, to genomes

This article will review recent impact of massively parallel next-generation sequencing (NGS) in our understanding and treatment of cancer. While whole exome sequencing (WES) remains popular and effective as a method of genetically profiling different cancers, advances in sequencing technology has e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Tony, Pajaro-Van de Stadt, Stefan Hans, Yeat, Nai Chien, Lin, Jimmy C.-H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469892/ https://www.ncbi.nlm.nih.gov/pubmed/26136771 http://dx.doi.org/10.3389/fgene.2015.00215

Ejemplares similares

Identification of Genomic Alterations in Thai Patients With Colorectal Cancer Using Next-Generation Sequencing-Based Multigene Cancer Panel
por: Jinda, Worapoj, et al.
Publicado: (2023)

Applications for next-generation sequencing in fish ecotoxicogenomics
por: Mehinto, Alvine C., et al.
Publicado: (2012)

Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing
por: Dolled-Filhart, Marisa P., et al.
Publicado: (2013)

Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels
por: LaDuca, Holly, et al.
Publicado: (2017)

Application of Next Generation Sequencing for personalized medicine for sudden cardiac death
por: Morini, Elena, et al.
Publicado: (2015)

Molecular Portrait of GISTs Associated With Clinicopathological Features: A Retrospective Study With Molecular Analysis by a Custom 9-Gene Targeted Next-Generation Sequencing Panel
por: Qian, Haoran, et al.
Publicado: (2022)

Genomic Selection in the Era of Next Generation Sequencing for Complex Traits in Plant Breeding
por: Bhat, Javaid A., et al.
Publicado: (2016)

Genetic Analysis Using a Next Generation Sequencing-Based Gene Panel in Patients With Skeletal Dysplasia: A Single-Center Experience
por: Kim, Su Jin, et al.
Publicado: (2021)

The Usefulness of a Targeted Next Generation Sequencing Gene Panel in Providing Molecular Diagnosis to Patients With a Broad Spectrum of Neurodevelopmental Disorders
por: Mellone, Simona, et al.
Publicado: (2022)

Analytical validation and implementation of a pan cancer next-generation sequencing panel, CANSeq(TM)Kids for molecular profiling of childhood malignancies
por: Schilter, Kala F., et al.
Publicado: (2023)

Corrigendum: Molecular Portrait of GIST Associated With Clinicopathological Features: A Retrospective Study With Molecular Analysis by a Custom 9-Gene Targeted Next-Generation Sequencing Panel
por: Qian, Haoran, et al.
Publicado: (2022)

The Use of Next-Generation Sequencing in Movement Disorders
por: Krebs, Catharine E., et al.
Publicado: (2012)

Statistics for Next Generation Sequencing – Meeting Report
por: Wu, Hao, et al.
Publicado: (2012)

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort
por: Klein, Kathrin, et al.
Publicado: (2019)

Diagnostic Yield of a Targeted Next-Generation Sequencing Gene Panel for Pediatric-Onset Movement Disorders: A 3-Year Cohort Study
por: Graziola, Federica, et al.
Publicado: (2019)

Multi-genome alignment for quality control and contamination screening of next-generation sequencing data
por: Hadfield, James, et al.
Publicado: (2014)

An additional whole-exome sequencing study in 102 panel-undiagnosed patients: A retrospective study in a Chinese craniosynostosis cohort
por: Chen, Jieyi, et al.
Publicado: (2022)

Clinical Application of Whole Exome Sequencing for Monogenic Disorders in PICU of China
por: Liu, Yingchao, et al.
Publicado: (2021)

Application of next-generation sequencing for the high-resolution typing of MHC-B in Korean native chicken
por: Ediriweera, Thisarani Kalhari, et al.
Publicado: (2022)

Next-Generation Sequencing for Binary Protein–Protein Interactions
por: Suter, Bernhard, et al.
Publicado: (2015)

Next Generation Sequencing Methods for Diagnosis of Epilepsy Syndromes
por: Dunn, Paul, et al.
Publicado: (2018)

Targeted Next-Generation Sequencing in the Diagnosis of Facial Dysostoses
por: Bukowska-Olech, Ewelina, et al.
Publicado: (2020)

Diagnostic application of exome sequencing in Chinese children with suspected inherited kidney diseases
por: Gao, Min, et al.
Publicado: (2023)

Next-generation development and application of codon model in evolution
por: Gupta, Manoj Kumar, et al.
Publicado: (2023)

A review of study designs and statistical methods for genomic epidemiology studies using next generation sequencing
por: Wang, Qian, et al.
Publicado: (2015)

Genomic analysis of a Palestinian family with inherited cancer syndrome: a next-generation sequencing study
por: Fares, Eman, et al.
Publicado: (2023)

Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients
por: Malapelle, Umberto, et al.
Publicado: (2017)

Mammalian miRNA curation through next-generation sequencing
por: Brown, Miguel, et al.
Publicado: (2013)

From next-generation sequencing to systematic modeling of the gut microbiome
por: Ji, Boyang, et al.
Publicado: (2015)

Next Generation Sequencing and Bioinformatics Analysis of Family Genetic Inheritance
por: Kanzi, Aquillah M., et al.
Publicado: (2020)

Integrating CRISPR-Cas and Next Generation Sequencing in Plant Virology
por: Mushtaq, Muntazir, et al.
Publicado: (2021)

Editorial: Next Generation Sequencing (NGS) for Rare Diseases Diagnosis
por: Yang, Xiu-An
Publicado: (2021)

Next-generation sequencing improves precision medicine in hearing loss
por: Imizcoz, T., et al.
Publicado: (2023)

A tailored next‐generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas
por: Higa, Nayuta, et al.
Publicado: (2020)

Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling
por: Chua, Eng Wee, et al.
Publicado: (2016)

Rapid Trio Exome Sequencing for Autosomal Recessive Renal Tubular Dysgenesis in Recurrent Oligohydramnios
por: Lin, Shin-Yu, et al.
Publicado: (2021)

Advancing Personalized Medicine Through the Application of Whole Exome Sequencing and Big Data Analytics
por: Suwinski, Pawel, et al.
Publicado: (2019)

Now and Next-Generation Sequencing Techniques: Future of Sequence Analysis Using Cloud Computing
por: Thakur, Radhe Shyam, et al.
Publicado: (2012)

A Scheduling Algorithm for Computational Grids that Minimizes Centralized Processing in Genome Assembly of Next-Generation Sequencing Data
por: Lima, Jakelyne, et al.
Publicado: (2012)

Integration of Next-Generation Sequencing Based Multi-Omics Approaches in Toxicogenomics
por: Jayapal, Manikandan
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_oh7bm94n066agmlu9f39cl44b3