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Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

Programmable nucleases, which include zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and RNA-guided engineered nucleases (RGENs) repurposed from the type II clustered, regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9)...

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Detalles Bibliográficos
Autores principales:	Koo, Taeyoung, Lee, Jungjoon, Kim, Jin-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Minireview
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469905/ https://www.ncbi.nlm.nih.gov/pubmed/25985872 http://dx.doi.org/10.14348/molcells.2015.0103

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