The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis

Hypoxia-inducible factor (HIF) is a key regulator of tumor growth and angiogenesis. Recent studies have shown that, BIX01294, a G9a histone methyltransferase (HMT)-specific inhibitor, induces apoptosis and inhibits the proliferation, migration, and invasion of cancer cells. However, not many studies...

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Detalles Bibliográficos
Autores principales: Oh, Su Young, Seok, Ji Yoon, Choi, Young Sun, Lee, Sung Hee, Bae, Jong-Sup, Lee, You Mie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469910/
https://www.ncbi.nlm.nih.gov/pubmed/26013382
http://dx.doi.org/10.14348/molcells.2015.0026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469910/
https://www.ncbi.nlm.nih.gov/pubmed/26013382
http://dx.doi.org/10.14348/molcells.2015.0026

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