HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression

Cytotoxic T lymphocyte (CTL) responses against the HIV Gag protein are associated with lowering viremia; however, immune control is undermined by viral escape mutations. The rapid viral mutation rate is a key factor, but recombination may also contribute. We hypothesized that CTL responses drive the...

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Detalles Bibliográficos
Autores principales: Chang, Chih-Hao, Kist, Nicolaas C., Chester, Tammy L. Stuart, Sreenu, Vattipally B., Herman, Melissa, Luo, Ma, Lunn, Daniel, Bell, John, Plummer, Francis A., Ball, T. Blake, Katzourakis, Aris, Iversen, Astrid K. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469978/
https://www.ncbi.nlm.nih.gov/pubmed/26082240
http://dx.doi.org/10.1038/srep11253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469978/
https://www.ncbi.nlm.nih.gov/pubmed/26082240
http://dx.doi.org/10.1038/srep11253

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